Not only had 50 Cent taken Ja Rule's place at the top of the rap game, but he had also taken Irv Gotti's place at the top of the music industry. G-Unit Records was going full speed ahead and 50 Cent wanted to land a coup. Despite being behind bars, Shyne fought his way off of Bad Boy Records.
After being released from Bad Boy, Shyne prepared to record a new album. 50 Cent realized the following that Shyne had and he wanted to sign him to G-Unit. The plan was to have Shyne record with all of the G-Unit producers. When approached by the Unit, Shyne turned them down.
50 Cent felt slighted by what Shyne had done, but he had no interest in feuding with him. In the end, Shyne would sign a one-album deal with Def Jam. Because no one was willing to openly work with Shyne, Irv Gotti reached out to him. Ja Rule helped him to write a bulk of his songs and Gotti helped to produce a few tracks off of his album. 50 Cent felt that anyone who worked with Ja Rule, Irv Gotti, or Ashanti were against him and his movement. This led to 50 Cent dissing Shyne and they have gone back and forth ever since.
Following the feuds between Fat Joe, Jadakiss, Nas, and The Game, 50 Cent would soon leave Shyne alone, but the feelings are still bitter. Fresh off of his release from prison, Shyne has dissed 50 Cent. His new track is called "There Will Be Blood" and it takes on the entire G-Unit crew. Following the release of the diss record, Lloyd Banks stepped in to defend G-Unit. Shyne said that his main focus is to put an official end to the reign of G-Unit. Since his release, Shyne has worked with Game and has realigned with Murder Inc.